明朝天启年间，左都御史杨涟(🍩)因得罪魏忠贤含(hán )冤入(rù )狱，魏(wèi )忠(🍥)贤授意(yì )东(dōng )(🎹)厂(chǎng )(🆖)及锦衣卫秘密将杨家灭(🥩)门(💤)，徐长(📿)卿受王(wáng )(⏬)冬青所(suǒ )托秘密救(jiù )(📼)援(yuán )(😎)杨(yáng )(🚤)涟孙女(🐿)杨紫萱，长卿舍身护送紫萱从应山府逃(táo )到龙泉(quán )村同仁医馆投靠刘谦，刘谦感念恩师杨涟恩(🕕)情，将紫萱收(shōu )作关门弟子细心照顾(gù )并传授(🛑)其(⏯)医学知识，此(🦗)后几个人(rén )将(jiāng )医馆(guǎn )生意打理(lǐ )(🔝)的井井(🏂)有(🙌)条，没想(🙄)到(㊙)却引来同(💪)行郎中(zhōng )吴(wú )南星的(🥫)嫉妒，最后惊(jīng )动魏忠贤(xián )党羽，魏忠(zhōng )贤(xián )得(dé )知杨紫(zǐ )萱踪迹派(pài )(🕯)出多批杀手奔(❕)医(💝)馆(guǎn )(💹)而来，只为将(🛎)杨家孤(gū )女(nǚ )紫萱和账(zhàng )本(🐛)（杨(⛏)涟所(suǒ )留魏忠贤通敌）一同(📟)斩(🐩)草除根…(🏒)…江湖风云又(yòu )起。